Document Type

Article

Publication Date

2026

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disorder that is present in adults and is characterized by progressive cyst development. It leads to chronic kidney disease (CKD) and end-stage renal disease (ESRD) due to loss of renal function. This case presents a 54-year-old male with known ADPKD and nephrolithiasis who presented with left flank pain and hypertension. Ultrasound evaluation demonstrated enlarged bilateral kidneys with numerous cysts replacing normal renal tissue and a kidney stone within the left kidney. For management, the patient was placed on medications and has been on the transplant list. This case highlights the importance of diagnosing and monitoring ADPKD to help assess progression and preserve renal function. Continued research is needed to improve access to care, optimize surveillance strategies, and develop therapies aimed at slowing disease progression and improving patient outcomes.

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