Date of Award


Document Type



College of Nursing

Degree Name

Doctor of Nursing Practice (DNP)

Project Mentor

Therry Eparwa


Leanna Standish


Mental health conditions including depression, anxiety, and post-traumatic stress disorder impact the lives of almost a billion people worldwide. The current standard pharmacological interventions offer limited benefits, but new research in ketamine-assisted psychotherapy (KAP) has shown promising outcomes. This study sought to add to the existing body of research regarding KAP by measuring whether depression, anxiety, and/or spirituality scores improved significantly in participants after one KAP session by measuring Patient Health Questionnaire-9 (PHQ~9) scores, General Anxiety Disqrder-7 {GAD-7), and National Institute of Health Healing Experience of All Life Stressors (NIHtHEALS) scores, respectively. A retrospective chart review performed on clinical data from 15 participants from the Advanced Integrative Medical Science (AIMS) Institute in Seattle, Washington showed that improvements in PHQ-9 and NIHHEALS scores were statistically significant after one KAP session, but there was not a statistically significant improvement to GAD-7 scores following one KAP session. Further research should be conducted to determine whether additional sessions contribute to any significant improvement to GAD-7 scores or greater and sustained improvements to PHQ-9 and NIH-HEALS scores.